Over the months that followed, Dane remained remarkably open about his condition. In interviews, he described ALS as a “nasty, unforgiving disease,” and explained that his symptoms began subtly — with weakness in his right hand that he initially dismissed as strain from texting.
On Good Morning America, Dane shared the difficult journey that followed:
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His right arm completely stopped functioning.
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His left arm began weakening soon after.
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By the time of the interview, he predicted he might lose the use of his left arm within “a couple more months.”
The diagnostic process itself took nine months as specialists tried to understand what was happening. In the end, it was clear: ALS was progressing aggressively.
Despite the emotional toll, the former Grey’s Anatomy star has become a strong advocate for ALS awareness — speaking honestly about the condition, its impact, and the importance of early detection.
A Difficult Fall and a Missed Reunion
In October, Dane suffered a serious fall that sent him to the hospital, forcing him to cancel his planned appearance at the Grey’s Anatomy cast reunion during the Emmy Awards.
Fans were disappointed, but many expressed overwhelming support, grateful simply to hear updates about his health.
Returning to Acting With a Role That Reflected Reality
Behind the scenes, something remarkable was developing.
The creators of Brilliant Minds had written an emotional holiday episode exploring ALS — and invited Eric Dane to portray a character living with the disease.
The role resonated deeply.
Dane played a firefighter and 9/11 hero who, after years of service, must confront the reality of an ALS diagnosis. One scene required him to record a message about seeking help, accepting vulnerability, and facing the unknown with courage.
The moment was powerful on screen — but even more extraordinary off screen.
Show creator Michael Grassi spoke with USA Today about the moment Dane completed one of the most emotional scenes:
“He essentially got a 10-minute standing ovation. I’ve never seen anything like it.”
According to Grassi, dozens of cast and crew members rose to their feet, many with tears in their eyes, applauding Dane’s bravery, honesty, and heart.
“It was beautiful, and it was real,” he said.
“His character was showing bravery, but Eric was showing real-life bravery too. It takes enormous courage to share this part of yourself with the world.”
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