Conditions that make the blood more likely to clot, such as thrombophilia, can cause blood to pool or get backed up in tiny vessels—leading to discoloration in the skin.
5. Medication Side Effects
Believe it or not, certain prescription drugs can contribute to livedo-like skin changes. These may include:
- Medications for high blood pressure
- Some Parkinson’s treatments
- Even certain hormonal therapies
6. Rare but Serious Conditions
Some rare disorders, such as Sneddon’s syndrome, polyarteritis nodosa, or cholesterol crystal embolism, may present with Livedo Reticularis along with other symptoms like strokes or nerve pain. These require urgent evaluation.
Symptoms to Watch For: When It’s More Than Just Skin Deep
The most obvious sign is, of course, the patterned discoloration. But there are other symptoms that may come along, especially if the condition is linked to something systemic:
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