Disappearance: In May 2005, 18-year-old Natalee Holloway vanished on a graduation trip to Aruba. She was last seen leaving a nightclub with Joran van der Sloot.WikipediaTeen Vogue
Investigation: Despite high-profile media attention and repeated investigations, no remains were found. Natalee was declared legally dead in 2012.Teen VogueWikipediaAP News
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