End-stage kidney failure (ESRF) or disease (ESRD), or simply kidney failure, is the fifth and final stage of chronic kidney disease (CKD) progression. At this point, you need dialysis or kidney transplant in order to survive.
Kidney failure occurs when the kidneys fail to function properly and are unable to effectively filter toxins, manage blood pressure, and regulate electrolyte levels. Until recently, kidney failure was related to old age, but sadly, the disease affects more and more young adults in recent years.